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In 1935, the present Natural Sciences program of the Rockefeller Foundation is to assist in research related to understanding somatic behavior and aid is given to projects in experimental biology. Weaver interviews professionals in the field of natural sciences and tours universities and research facilities to assess Rockefeller Foundation programs in experimental biology. He tours Cambridge for new natural science research programs. The diary includes an itinerary for a European trip 1-27 May 1935.

The diary is arranged by interview and visit. Weaver discusses research interests and program issues with various professionals in the field of natural sciences. He tours American universities on behalf of the Rockefeller Foundation to assess experimental biology programs, interests and state of natural science education.

The Rockefeller Foundation Division of Natural Sciences focuses on experimental biology and adapting to the needs of World War II. The diary documents artifact production of antibodies, a trip to Mexico to tour the Rockefeller Foundation Mexican Agricultural Program and includes a program for "6th International congress for Applied Mechanics."